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Acute Effects on the Counts of Innate and Adaptive Immune Response Cells After 1 Month of Taoist Qigong Practice
Tipo Artículo en revista científica Autor Francisca M. Vera Autor Juan M. Manzaneque Autor Francisco M. Rodríguez Autor Rebecca Bendayan Autor Nieves Fernández Autor Antonio Alonso Publicación International Journal of Behavioral Medicine ISSN 1532-7558 Fecha Sep 14, 2015 Adicional PMID: 26370102 Abrev. de la revista Int J Behav Med DOI 10.1007/s12529-015-9509-8 Catálogo de biblioteca PubMed Idioma ENG Resumen BACKGROUND: Qigong is an ancient form of health maintenance, dating back thousands of years, which is part of Traditional Chinese Medicine. Numerous physical as well as mental benefits have been classically ascribed to this traditional mind-body method which integrates slow body movements, breathing, and meditation. Albeit we have already reported an immunomodulatory action of qigong in other investigations, measures were then assessed 1 day after the qigong program ended. PURPOSE: The aim of the present study was to assess the acute effects of Taoist qigong practice on immune cell counts in healthy subjects 1 h after training. METHOD: Forty-three healthy subjects participated in the study of whom 25 were randomly allocated to the experimental group and 18 to the control group. The experimental subjects underwent daily qigong training for 1 month. Blood samples for the quantification of immune parameters (number and percentage of monocytes, neutrophils, eosinophils, total lymphocytes, B lymphocytes, and natural killer (NK) cells) were taken the day before the experiment commenced and 1 h after the last session of the training program ended. As statistical analysis, analysis of covariance (ANCOVA) was performed. RESULTS: Statistically significant differences were found between the experimental and control groups, with the experimental group showing higher values in the number (p = 0.006) and the percentage (p = 0.04) of B lymphocytes, as well as lower values in the percentage of NK cells (p = 0.05), as compared to control. CONCLUSION: This study demonstrates that Taoist qigong is able to exert acute immunomodulatory effects on components of both innate as well as adaptive immune response. Fecha de adición 22/10/2015 13:24:00 Modificado 22/10/2015 13:24:00 Marcas:
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Assessment of long-term cognitive impairment after off-pump coronary-artery bypass grafting and related risk factors
Tipo Artículo en revista científica Autor Luis M. Pérez-Belmonte Autor Carlos M. San Román-Terán Autor Manuel Jiménez-Navarro Autor Miguel A. Barbancho Autor José M. García-Alberca Autor José P. Lara Volumen 16 Ejemplar 3 Páginas 263.e9-11 Publicación Journal of the American Medical Directors Association ISSN 1538-9375 Fecha Mar 2015 Adicional PMID: 25648462 Abrev. de la revista J Am Med Dir Assoc DOI 10.1016/j.jamda.2014.12.001 Catálogo de biblioteca PubMed Idioma eng Resumen OBJECTIVES: To assess cognitive impairment after off-pump coronary-artery bypass grafting, with a particular emphasis on long-term follow-up and related risk factors. DESIGN: Prospective study. SETTING: Virgen de la Victoria University Hospital, Málaga, Spain. PARTICIPANTS: Participants were 36 patients undergoing off-pump coronary-artery bypass grafting. MEASUREMENTS: Changes in the neuropsychological test battery administered from before to after surgery (1, 6, and 12 months). Postoperative cognitive impairment was defined by a significant decrease. RESULTS: A significantly multidomain (attention-executive functions, P < .01; immediate and delayed memory, P < .001; and verbal fluency, P < .05) postoperative cognitive impairment was shown, being maximum at 6 months (more than 50% of patients) and still presented at 12 months (more than 30% of patients), but partially recovered. Related risk factors as smoking (P < .01), diabetes mellitus (P < .01), peripheral arteriopathy (P < .01), obesity (P < .05), lower hematocrit (P < .01), and hemoglobin (P < .05) levels and diastolic blood pressure (P < .05) were identified as predictors of cognitive impairment. Better New York Heart Association class (P < .01) and less severity of angina (P < .01) were associated with partial postoperative recovering. CONCLUSION: A multidomain long-term postoperative cognitive impairment and a partial neurocognitive recovering were detected after off-pump coronary-artery bypass grafting and were associated with several nonspecific surgery factors. These findings may be useful when counseling patients before surgery and suggest the importance of long-term neurocognitive evaluation. Fecha de adición 13/7/2015 9:23:58 Modificado 13/7/2015 9:23:58 Adjuntos
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Bilateral acute retinal necrosis due to varicella zóster virus in an elderly patient
Tipo Artículo en revista científica Autor O. Villena-Irigoyen Autor L. Echevarría-Lucas Autor M. Castro-Gómez Autor R. M. Bellido-Muñoz Publicación Archivos De La Sociedad Espanola De Oftalmologia ISSN 1989-7286 Fecha Mar 25, 2015 Adicional PMID: 25817963 Abrev. de la revista Arch Soc Esp Oftalmol DOI 10.1016/j.oftal.2015.02.012 Catálogo de biblioteca PubMed Idioma ENG, SPA Resumen CASE REPORT: The case is reported of acute retinal necrosis with bilateral involvement due to Varicella Zoster virus in a 77 year-old man. Polymerase chain reaction (PCR) of aqueous humor was positive for Varicella Zoster virus (VZV). He developed a Kyrieleis' vasculitis a month after the starting treatment, when the PCR analysis was negative. DISCUSSION: PCR is a quick and safe technique, with a high sensitivity and specificity of 97%, useful to diagnose and monitor the viral activity. The intervention must be urgent, due to the dramatically rapid evolution. Oral famciclovir oral is good alternative owing to its bioavailability. Fecha de adición 22/10/2015 13:24:00 Modificado 22/10/2015 13:24:00 Marcas:
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Clinical, virological and phylogenetic characterization of a multiresistant HIV-1 strain outbreak in naive patients in southern Spain
Tipo Artículo en revista científica Autor I. Viciana Autor C. M. González-Domenech Autor R. Palacios Autor M. Delgado Autor A. Del Arco Autor F. Tellez Autor F. Jarilla Autor S. Fernández Autor E. Clavijo Autor J. Santos Publicación The Journal of Antimicrobial Chemotherapy ISSN 1460-2091 Fecha Oct 19, 2015 Adicional PMID: 26483513 Abrev. de la revista J. Antimicrob. Chemother. DOI 10.1093/jac/dkv332 Catálogo de biblioteca PubMed Idioma ENG Resumen BACKGROUND: We describe the characteristics of an HIV-1 strain with six viral reverse transcriptase mutations (D67N, T69N/D, V118I, V179D, T215S and K219Q), which we have called the Malaga strain. This strain was detected in treatment-naive patients from southern Spain. METHODS: The study was undertaken at the Virgen de la Victoria Hospital, Malaga, a reference centre for the study of HIV-1 genotype resistance in Andalusia (the 'Costa del Sol'), Spain. Genotypic resistance testing was done in an automated sequencer. Phylogenetic analysis was performed using a 630 bp region of the reverse transcriptase with the mutations mentioned. RESULTS: Between 2007 and 2014, we detected the Malaga strain in 30 treatment-naive patients. All were MSM, seen at five hospitals on the Costa del Sol. In all cases, the HIV-1 was subtype B with viral tropism R5. Phylogenetic analysis based on the reverse transcriptase sequence showed consistent grouping (with a bootstrap value of the common node of 100%) of the isolates that shared the mutation pattern mentioned. This strain has not been detected elsewhere or in previously treated patients. All of the patients treated with first-line combination ART responded. CONCLUSIONS: We report a cluster of an HIV-1 strain with multiple resistance mutations that was transmitted over a period of >8 years, affecting 30 naive patients from the same geographical area. The strain was susceptible to first-line combination ART. Fecha de adición 22/10/2015 13:24:00 Modificado 22/10/2015 13:24:00 Adjuntos
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[Combined hamartoma of the retina and retinal pigment epithelium. Anti-VEGF treatment of the associated choroidal neovascular membranes]
Tipo Artículo en revista científica Autor L. Echevarría Autor O. Villena Autor T. Nievas Autor R. Bellido Volumen 90 Ejemplar 2 Páginas 87-93 Publicación Archivos De La Sociedad Española De Oftalmología ISSN 1989-7286 Fecha Feb 2015 Adicional PMID: 25499584 Abrev. de la revista Arch Soc Esp Oftalmol DOI 10.1016/j.oftal.2014.09.017 Catálogo de biblioteca PubMed Idioma spa Resumen CASE REPORT: A 58 year-old female was diagnosed with a juxtapapillary combined hamartoma of the retina and retinal pigment epithelium (CHR-RPE) in her left eye 14 years ago. Her visual acuity in that eye was 20/20. Recently, she came to our department with a sudden visual loss and metamorphopsis in her left eye. After performing funduscopy, angiography and OCT, she was diagnosed with choroidal neovascular membrane (CNVM) at lesion border, and started on antiangiogenic therapy. DISCUSSION: CHR-RPE, despite being a benign condition, may become complicated with severe visual impairment. Antiangiogenic therapy provides a good alternative to photodynamic therapy or laser photocoagulation for treatment of CNVM, avoiding adding iatrogenesis from these treatment to the complications associated with this pathology. Fecha de adición 13/7/2015 9:25:01 Modificado 13/7/2015 9:25:01 Adjuntos
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Drug utilization pattern in children and off-label use of medicines in a pediatric intensive care unit
Tipo Artículo en revista científica Autor E. Blanco-Reina Autor A. F. Medina-Claros Autor M. A. Vega-Jiménez Autor R. Ocaña-Riola Autor E. I. Márquez-Romero Autor Á Ruiz-Extremera Publicación Medicina Intensiva / Sociedad Espanola De Medicina Intensiva Y Unidades Coronarias ISSN 1578-6749 Fecha Jan 9, 2015 Adicional PMID: 25583042 Abrev. de la revista Med Intensiva DOI 10.1016/j.medin.2014.11.007 Catálogo de biblioteca PubMed Idioma ENG, SPA Resumen OBJECTIVE: This study aims to assess the prescription profile and license status of drugs used in a neonatal and pediatric intensive care unit (NPICU). METHODS: A prospective observational study was conducted on a dynamic cohort of children admitted to an NPICU (N=81) in a tertiary hospital (Granada, Spain). All prescriptions were classified as off-label or unlicensed based on the summary of product characteristics (SPC). RESULTS: Of a total of 601 prescriptions, the patients received a mean of 7.4±6 drugs each. The most commonly prescribed drugs corresponded to classes J (anti-infectious, systemic use) N (nervous system) and C (cardiovascular). A little over one-half of the prescriptions were off-label (52%), usually due to dosages differing from the SPC recommendations (79%), followed by different indications (13.5%), age (5%) and administration route (2.5%). In this NPICU, unlicensed usage represented only 5% of all prescriptions. CONCLUSIONS: This study contributes data on prescription of this kind in a Spanish NPICU, revealing at least one off-label prescription in 89% of the children and at least one unlicensed use in 22.3%. These are high figures, but are to be expected given the inclusion of newborn infants and the critical care setting. Even though such usage follows clinical protocols, we underscore the dual need to base treatment on the best available evidence, and to upgrade the SPC accordingly. Fecha de adición 13/7/2015 9:24:37 Modificado 13/7/2015 9:24:37 Adjuntos
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[Faecal calprotectin as an aid to the diagnosis of non-IgE mediated cow's milk protein allergy]
Tipo Artículo en revista científica Autor C. Trillo Belizón Autor E. Ortega Páez Autor A. F. Medina Claros Autor I. Rodríguez Sánchez Autor A. Reina González Autor R. Vera Medialdea Autor J. M. Ramón Salguero Publicación Anales De Pediatria (Barcelona, Spain: 2003) ISSN 1695-9531 Fecha Sep 2, 2015 Adicional PMID: 26342278 Abrev. de la revista An Pediatr (Barc) DOI 10.1016/j.anpedi.2015.07.007 Catálogo de biblioteca PubMed Idioma SPA Resumen INTRODUCTION: The aim of the study was to assess the use of faecal calprotectin (FCP) in infants with signs and symptoms of non-IgE-mediated cow's milk protein allergy (CMA) for both diagnosis and prediction of clinical response at the time of withdrawal of milk proteins. PATIENTS AND METHODS: A one year prospective study was conducted on 82 infants between 1 and 12 months of age in the Eastern area of Málaga-Axarquía, of whom 40 of them had been diagnosed with non-IgE-mediated CMA (with suggestive symptoms and positive response to milk withdrawal), 12 not diagnosed with CMA, and 30 of them were the control group. FCP was measured at three different times: time of diagnosis, and one and three months later. ANOVA for repeated measures, nominal logistic regression and ROC curves were prepared using the SPSS.20 package and Medcalc. RESULTS: Differences between diagnostic and control groups were assessed: there was a statistically significant relationship (p<.0001) between high FCP levels and infants suffering CMA, as well as the levels at time of diagnosis, 1 and 3 months (p <.001). A ROC curve was constructed between FCP levels and diagnosis of CMA, with 138 ug/g, with the best cut-off being with an area under the curve of 0.89. However, it is only 0.68 to predict a clinical response. CONCLUSIONS: FCP levels lower than 138ug/g could be useful to rule out non-IgE-mediated CMA diagnosis. Calprotectin is not a good test to predict clinical response to milk withdrawal. Fecha de adición 22/10/2015 13:24:00 Modificado 22/10/2015 13:24:00 Marcas:
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Short- and long-term outcomes of surgery for severe tricuspid regurgitation
Tipo Artículo en revista científica Autor Jorge Rodríguez-Capitán Autor Juan J. Gómez-Doblas Autor Leticia Fernández-López Autor Raúl López-Salguero Autor Manuel Ruiz Autor Inés Leruite Autor Fernando Cabrera-Bueno Autor María J. Mataró-López Autor Gemma Sánchez-Espín Autor José M. Melero-Tejedor Autor Carlos Porras-Martín Autor Miguel Such Autor Eduardo de Teresa Volumen 66 Ejemplar 8 Páginas 629-635 Publicación Revista Española De Cardiología (English Ed.) ISSN 1885-5857 Fecha Aug 2013 Adicional PMID: 24776331 Abrev. de la revista Rev Esp Cardiol (Engl Ed) DOI 10.1016/j.rec.2013.02.002 Catálogo de biblioteca PubMed Idioma eng Resumen INTRODUCTION AND OBJECTIVES: There is little data available for Spain on the outcomes of surgical treatment for severe tricuspid regurgitation. The aim of this study was to analyze clinical and echocardiographic outcomes in a series of patients who received surgical treatment for severe tricuspid regurgitation and to compare outcomes according to the operative approach to valve repair or replacement. METHODS: Retrospective study in 119 consecutive patients with severe tricuspid regurgitation undergoing valve surgery between April 1996 and February 2010. RESULTS: A total of 61 ringless and 23 ring annuloplasties were performed and 11 bioprostheses and 24 mechanical prostheses were implanted. Perioperative mortality was 18.5% and was associated with age and cardiopulmonary bypass time. During clinical follow-up (median, 41 [interquartile range, 24-89] months), 2 reoperations were required in the ring annuloplasty and mechanical prosthesis groups; prosthetic thrombosis was diagnosed in 4 patients in the latter group. Total mortality after follow-up was 29.9% and was associated with age>70 years and extracorporeal circulation time. The emergence of new severe tricuspid regurgitation was associated with age and ringless annuloplasty (P=.04). CONCLUSIONS: Ringless repair was significantly associated with recurrence of severe tricuspid regurgitation. The use of mechanical prostheses was associated with a high rate of thrombosis. No significant differences in perioperative or total mortality were found between the different methods used for repair or valve replacement. Fecha de adición 13/7/2015 9:22:23 Modificado 13/7/2015 9:22:23 Marcas:
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[Thyroid dysfunction in pregnancy. Consensus document. Andalusian Society of Endocrinology and Nutrition (SAEN).]
Tipo Artículo en revista científica Autor P. Santiago Fernández Autor S. González-Romero Autor T. Martín Hernández Autor E. Navarro González Autor I. Velasco López Autor M. C. Millón Ramírez Publicación Semergen / Sociedad Espanola De Medicina Rural Y Generalista ISSN 1578-8865 Fecha Feb 18, 2015 Adicional PMID: 25700854 Abrev. de la revista Semergen DOI 10.1016/j.semerg.2014.12.011 Catálogo de biblioteca PubMed Idioma SPA Resumen A position statement on the diagnosis and treatment of thyroid dysfunction in pregnancy has been agreed on behalf of The Sociedad Andaluza de Endocrinología y Nutrición (SAEN), based on a review of the literature to date and all good clinical practice guidelines. The document is set out in different sections as regards the diagnosis and treatment of, overt and subclinical hypo- and hyperthyroidism, isolated hypothyroxinaemia and postpartum thyroiditis. It also justifies the implementation of universal screening for thyroid dysfunction in pregnancy, and provides practitioners who care for these patients with tool for rational decision making. Fecha de adición 13/7/2015 9:23:28 Modificado 13/7/2015 9:23:28 Adjuntos
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Using dermoscopy to assess diagnostic criteria of neurofibromatosis
Tipo Artículo en revista científica Autor Elisabeth Gómez Moyano Autor Leandro Martínez Pilar Autor Marina Rodriguez Calvo de Mora Autor Maria Virginia Herrero Garcia Autor Antonio Francia Autor Daniel Jesús Godoy Diaz Autor Angel Vera Casaño Volumen 73 Ejemplar 1 Páginas e17-18 Publicación Journal of the American Academy of Dermatology ISSN 1097-6787 Fecha Jul 2015 Adicional PMID: 26089063 Abrev. de la revista J. Am. Acad. Dermatol. DOI 10.1016/j.jaad.2015.03.053 Catálogo de biblioteca PubMed Idioma eng Fecha de adición 13/7/2015 9:21:46 Modificado 13/7/2015 9:21:46 Adjuntos
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Using dermoscopy to assess diagnostic criteria of neurofibromatosis
Tipo Artículo en revista científica Autor Elisabeth Gómez Moyano Autor Leandro Martínez Pilar Autor Marina Rodriguez Calvo de Mora Autor Maria Virginia Herrero Garcia Autor Antonio Francia Autor Daniel Jesús Godoy Diaz Autor Angel Vera Casaño Volumen 73 Ejemplar 1 Páginas e17-18 Publicación Journal of the American Academy of Dermatology ISSN 1097-6787 Fecha Jul 2015 Adicional PMID: 26089063 Abrev. de la revista J. Am. Acad. Dermatol. DOI 10.1016/j.jaad.2015.03.053 Catálogo de biblioteca PubMed Idioma eng Fecha de adición 22/10/2015 13:24:00 Modificado 22/10/2015 13:24:00 Marcas:
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[Verrocous mass on the tongue: oral florid papillomatosis]
Tipo Artículo en revista científica Autor Luis Miguel Pérez-Belmonte Autor Elisabeth Gómez-Moyano Autor Leticia Herrero-Lifona Autor Francisco Jiménez-Oñate Volumen 33 Ejemplar 2 Páginas 135-136 Publicación Enfermedades Infecciosas Y Microbiología Clínica ISSN 1578-1852 Fecha Feb 2015 Adicional PMID: 25037616 Abrev. de la revista Enferm. Infecc. Microbiol. Clin. DOI 10.1016/j.eimc.2014.04.011 Catálogo de biblioteca PubMed Idioma spa Título corto [Verrocous mass on the tongue Fecha de adición 13/7/2015 9:25:31 Modificado 13/7/2015 9:25:31 Adjuntos
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Tipo Artículo en revista Fecha de adición 23/9/2015 10:02:33 Modificado 23/9/2015 10:02:33
22/10/15
Publicaciones Axarquía 2015 (Octubre 2015)
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